Sorafenib

In the US, Sorafenib (sorafenib systemic) is a member of the following drug classes: multikinase inhibitors, VEGF/VEGFR inhibitors and is used to treat Hepatic Tumor, Hepatocellular Carcinoma, Renal Cell Carcinoma and Thyroid Cancer.

US matches:

• Sorafenib


• Sorafenib Tosylate

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01XE05

CAS registry number (Chemical Abstracts Service)

0284461-73-0

Chemical Formula

C21-H16-Cl-F3-N4-O3

Molecular Weight

464

Therapeutic Categories

Antineoplastic agent

Angiogenesis inhibitor

Tyrosine kinase inhibitor

Chemical Names

4-(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N²-methylpyridine-2-carboxamide (WHO)

4-{4-[3-(4-Chlor-3-trifluormethylphenyl)ureido]phenoxy}pyridin-2-carbonsäuremethylamid (IUPAC)

Foreign Names

• Sorafenibum (Latin)
• Sorafenib (German)
• Sorafénib (French)
• Sorafenib (Spanish)

Generic Names

• Sorafenib (OS: USAN)
• BAY 43-9006 (IS: Onyx, Bayer)
• Sorafenib tosylate (OS: USAN)
• Sorafenib tosylat (IS)

Brand Names

• Nexavar
  Bayer, Czech Republic; Bayer, Greece; Bayer, Slovenia; Bayer, Argentina; Bayer, Belgium; Bayer, Belize; Bayer, Canada; Bayer, Switzerland; Bayer, Chile; Bayer, Costa Rica; Bayer, Germany; Bayer, Denmark; Bayer, Dominican Republic; Bayer, Spain; Bayer, Finland; Bayer, United Kingdom; Bayer, Guatemala; Bayer, Honduras; Bayer, Croatia (Hrvatska); Bayer, Hungary; Bayer, Ireland; Bayer, Italy; Bayer, Mexico; Bayer, Nicaragua; Bayer, Norway; Bayer, Panama; Bayer, Sweden; Bayer, Slovakia; Bayer, El Salvador; Bayer, United States; Bayer AG, Luxembourg; Bayer Healthcare, Austria; Bayer Santé, France; Bayer Schering, Australia; Bayer Schering, Indonesia; Bayer Schering, Netherlands; Bayer Schering, South Africa

International Drug Name Search

Glossary

IUPAC	International Union of Pure and Applied Chemistry
IS	Inofficial Synonym
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name
WHO	World Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.